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VU 0357017 hydrochloride
CAS No. 1135242-13-5
VU 0357017 hydrochloride( VU0357017, VU-0357017, VU 0357017, CID 25010775 )
Catalog No. M17152 CAS No. 1135242-13-5
VU 0357017 hydrochloride is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM; Pec50: 6.37 ± 0.15).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 37 | In Stock |
|
| 5MG | 60 | In Stock |
|
| 10MG | 97 | In Stock |
|
| 25MG | 191 | In Stock |
|
| 50MG | 284 | In Stock |
|
| 100MG | 422 | In Stock |
|
| 500MG | 888 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameVU 0357017 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionVU 0357017 hydrochloride is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM; Pec50: 6.37 ± 0.15).
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DescriptionVU0357017, also known as CID 25010775, is a subtype-selective M1 muscarinic acetylcholine allosteric agonist.
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In Vitro——
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In VivoAnimal Model:Male Sprague?Dawley rats (380-420 g) were pretreated with scopolamine Dosage:1, 3, 10 mg/kg Administration:A single i.p.Result:Produced a significant reversal of the scopolamine-induced deficits at a dose of 10 mg/kg.
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SynonymsVU0357017, VU-0357017, VU 0357017, CID 25010775
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PathwayOthers
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TargetOther Targets
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RecptorM1 mAChR
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number1135242-13-5
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Formula Weight369.89
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Molecular FormulaC18H28ClN3O3
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 33 mg/mL 89.22 mM
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SMILESCCOC(=O)N1CCC(CC1)NCCNC(=O)c1ccccc1C.Cl
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Chemical Name4-[[2-[(2-methylbenzoyl)amino]ethyl]amino]-1-piperidinecarboxylic acid ethyl ester, monohydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Digby GJ, et al. ACS Chem Neurosci. 2012 Dec 19;3(12):1025-36.
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